Nefazodone hydrochloride
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Nefazodone hydrochloride



Serzone (Nefazodone) Side Effects, Interactions, Warning, Dosage

8.22.2017 | Ashley Kendal
Nefazodone hydrochloride
Serzone (Nefazodone) Side Effects, Interactions, Warning, Dosage

Nefazodone hydrochloride is a synthetically derived phenylpiperazine antidepressant. The chemical name for nefazodone hydrochloride is.

Anyone considering the use of SERZONE (nefazodone) or any other antidepressant in a child or adolescent must balance this risk with the clinical need. (See WARNINGS and PRECAUTIONS : Pediatric Use.) Pooled analyses of short-term (4 to 16 weeks) placebo-controlled trials of nine antidepressant drugs (SSRIs and others) in children and adolescents with major depressive disorder (MDD), obsessive compulsive disorder (OCD), or other psychiatric disorders (a total of 24 trials involving over 4400 patients) have revealed a greater risk of adverse events representing suicidal thinking or behavior (suicidality) during the first few months of treatment in those receiving antidepressants.

Nefazodone

5.19.2017 | Ashley Kendal
Nefazodone hydrochloride
Nefazodone

Nefazodone hydrochloride tablets should be discontinued if clinical signs or symptoms suggest liver failure (see PRECAUTIONS, Information for Patients).

Nefazodone hydrochloride is a synthetically derived phenylpiperazine antidepressant. The structural formula is:. The chemical name for Nefazodone hydrochloride is 2-[3-propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one monohydrochloride.

Patients should be advised to be alert for signs and symptoms of liver dysfunction (jaundice, anorexia, gastrointestinal complaints, malaise, etc.) and to report them to their doctor immediay if they occur.

Nefazodone is rapidly and compley absorbed but is subject to extensive metabolism, so that its absolute bioavailability is low, about 20%, and variable.

Nefazodone HCL

7.21.2017 | Sydney Carter
Nefazodone hydrochloride
Nefazodone HCL

Find patient medical information for Nefazodone Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

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Some products that may interact with this drug include: carbamazepine, eplerenone, ergot alkaloids (such as dihydroergotamine, ergonovine, ergotamine, methylergonovine ), ivabradine, lurasidone, pimozide, triazolam, alpha blockers (e.g., terazosin ), digoxin, fluoxetine, medications for high blood pressure, other antidepressants (e.g., trazodone, SSRIs such as fluoxetine), other drugs that can cause bleeding/bruising (e.g., anticoagulants such as heparin or warfarin, antiplaet drugs including NSAIDs such as ibuprofen ).

Nefazodone has rarely caused very serious (possibly fatal) liver disease.

Nefazodone, Serzone Drug Facts, Side Effects and Dosing

11.25.2017 | Sydney Carter
Nefazodone hydrochloride
Nefazodone, Serzone Drug Facts, Side Effects and Dosing

Information on the drug nefazodone (Serzone) prescribed for the treatment of depression. Side effects, drug interactions, and patient information is included.

Side effects depend on the medication prescribed. Drug interactions, warnings and precautions, and pregnancy and breastfeeding safety should be reviewed prior to taking any medication.

Get the facts on depression, mania and bipolar disorder. Learn causes, symptoms, diagnosis, and medical treatments for this very common mental health condition.

MedicineNet does not provide medical advice, diagnosis or treatment. See additional information.

Use the pill identifier tool on RxList.

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Nefazodone

6.20.2017 | Sydney Carter
Nefazodone hydrochloride
Nefazodone

Nefazodone is an antidepressant that was first marketed by Bristol-Myers Squibb in 1994. BMS withdrew it from the market by 2004 due to decreasing sales due.

In April 2004, BMS announced that it was going discontinue the sale of Serzone in the US in June 2004 and said that this was due to declining sales. By that time BMS had already withdrawn the drug from the market in Europe, Australia, New Zealand and Canada.

In 2003 Public Citizen filed a citizen petition asking the FDA to withdraw the marketing authorization in the US, and in early 2004 the organization sued the FDA to attempt to force withdrawal of the drug. The FDA issued a response to the petition in June 2004 and filed a motion to dismiss, and Public Citizen withdrew the suit.

Nefazodone was discovered by scientists at Bristol-Myers Squibb (BMS) who were seeking to improve on trazodone by reducing its sedating qualities.

Common and mild side effects of nefazodone reported in clinical trials more often than placebo include dry mouth (25%), sleepiness (25%), nausea (22%), dizziness (17%), blurred vision (16%), weakness (11%), lightheadedness (10%), confusion (7%), and orthostatic hypotension (5%).