Norpace (disopyramide phosphate) is an anti-arrhythmic drug available for oral administration in immediate-release and controlled-release capsules containing 100 mg or 150 mg of disopyramide base, present as the phosphate.
If a Q-T prolongation of greater than 25% is observed and if ectopy continues, the patient should be monitored closely, and consideration be given to discontinuing Norpace (disopyramide phosphate) or Norpace (disopyramide phosphate) CR.
home drugs a-z list side effects drug center norpace (disopyramide phosphate) drug.
3, FD&C Yellow No. 6, gelatin, lactose, talc, and titanium dioxide; the 150-mg capsule also contains FD&C Blue No.1. Inactive ingredients of Norpace (disopyramide phosphate) include corn starch, edible ink, FD&C Red No.
Norpace CR (disopyramide phosphate) Controlled-Release is supplied as specially prepared controlled-release beads in hard gelatin capsules containing either 100 mg or 150 mg of disopyramide base, present as the phosphate.
Gastrointestinal : nausea, pain/bloating/gas.
The recommended dosage for most adults is 600 mg/day given in divided doses (either 150 mg every 6 hours for immediate-release Nor-pace or 300 mg every 12 hours for Norpace (disopyramide phosphate) CR).
Norpace official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.
After the oral administration of 200 mg of disopyramide to 10 cardiac patients with borderline to moderate heart failure, the time to peak serum concentration of 2.3 ± 1.5 hours (mean ± SD) was increased, and the mean peak serum concentration of 4.8 ± 1.6 mcg/ml was higher than in healthy volunteers. In a second study of the oral administration of disopyramide to 7 patients with heart disease, including left ventricular dysfunction, the mean plasma half-life was slightly prolonged to 7.8 ± 1.9 hours (range of 5 to 9.5 hours).
This medication is used to treat certain types of serious (possibly fatal) irregular heartbeat, such as persistent ventricular tachycardia. It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Disopyramide is known as an anti-arrhythmic drug.
During pregnancy, this medication should be used only when clearly needed. Rarely, disopyramide may cause early labor during pregnancy. Discuss the risks and benefits with your doctor.
l your doctor right away if any of these rare but serioussymptoms of low blood sugar (such as shakiness with unusual hunger / headache / sweating ), signs of liver problems (such as persistent nausea / vomiting, stomach /abdominal pain, yellowing eyes / skin, dark urine), muscle weakness, worsening symptoms of heart failure (such as ankle /leg swelling, increased tiredness, increased shortness of breath when lying down).
Selected from data included with permission and ed by First Databank, Inc.
Physician reviewed Norpace patient information - includes Norpace description, dosage and directions.
low blood sugar, or diabetes;
Approval History 10+ years FDA approved 1977.
Version: 6.01. Cerner Multum, Inc.
little or no urinating, painful or difficult urination;
Disopyramide affects the way that your heart beats.
Generic Name: disopyramide (DYE soe PIR a mide) Brand Name: Norpace, Norpace CR.
Call your doctor at once if you have:
other heart rhythm medicines--encainide, flecainide, propranolol, propafenone, quinidine.
dry mouth, nose, or throat;
congestive heart failure, or if you have recently had a heart attack; low blood pressure;
Disopyramide may also be used for purposes not listed in this medication guide.
See also: Side effects (in more detail).
a new or a worsening irregular heartbeat pattern;
a serious heart condition such as "AV block" (unless you have a pacemaker).
Availability Rx Prescription only.
nausea, stomach pain, bloating; constipation;
Overdose symptoms may include trouble breathing, irregular heartbeats, and loss of consciousness.
Do not skip doses or change your dosing schedule without your doctor's advice.
Easy to read patient leaflet for Norpace. Includes indications, proper use, special instructions, precautions, and possible side effects.
Some medical conditions may interact with Norpace. l your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Generic Name: disopyramide (dye-soe-PEER-a-mide) Brand Name: Norpace.
Norpace is an antiarrhythmic. It works by stabilizing the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm (antiarrhythmic effect).
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Availability Rx Prescription only.
This may not be a complete list of all interactions that may occur.